| Waterloo is located along the "Avenue of the Saints," a Federal Interstate that connects Minneapolis /St. Paul, MN and St. Louis, MO. Waterloo has six major US cities within a 5-hour drive including: | |
| Minneapolis, MN | 3 ½ hour drive |
| Omaha, NE | 4 hour drive |
| Chicago, IL | 4 ½ hour drive |
| Milwaukee, WI | 4 ¾ hour drive |
| Kansas City, MO | 5 hour drive |
| St. Louis, MO | 5 hour drive |
Interstate Highway
- I-380
- I-80 (by way of I-380)
- I-35 (by way of US 20)
- US 20, 63, 218
- State 21, 57, 58, 281
- 22
- Chicago National/Illinois Central and Pacific
- Iowa Northern Railway
- Union Pacific
Waterloo Regional Airport
- The Waterloo Regional Airport can accommodate jets up to a Boeing 747.
- Commercial Carriers: American Airlines
- Flights per day: 2
